Grupa Badawcza Mechanizmów Neurodegeneracji
Publikacje

An Overview of Methods for Detecting eIF2α Phosphorylation and the Integrated Stress Response
Krzyzosiak A., Pitera A., Bertolotti A.
(2022) Methods Mol Biol. 2428:3-18

Vitamin A5/X controls stress-adaptation and prevents depressive-like behaviors in a mouse model of chronic stress
Krzyzosiak A., Podlesny-Drabiniok A., Vaz B., Alvarez R., Rühl R., de Lera AR., Krezel W.
(2021) Neurobiol Stress. Aug 3;15:100375

Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B
Krzyzosiak A., Sigurdardottir A., Luh L., Carrara M., Das I., Schneider K., and Bertolotti A.
(2018) Cell. Aug 23; 174(5), 1216–1228

Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington’s Disease and Other Neurodegenerative Disorders
Niewiadomska-Cimicka A., Krzyżosiak A., Ye T., Podleśny-Drabiniok A., Dembélé D., Dollé P., Krężel W.
(2017) Mol Neurobiol. Jul;54(5):3859-3878

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice
Rühl R., Krzyżosiak A., Niewiadomska-Cimicka A., Rochel N., Szeles L., Vaz B., Wietrzych-Schindler M., Álvarez S., Szklenar M., Nagy L., de Lera AR., Krężel W.
(2015) PLoS Genet. Jun 1;11(6):e1005213

Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit
Das I., Krzyzosiak A., Schneider K., Wrabetz L., D’Antonio M., Barry N., Sigurdardottir A., Bertolotti A.
(2015) Science. Apr 10;348(6231):239-42

An inducible chaperone adapts proteasome assembly to stress
Hanssum A., Zhong Z., Rousseau A., Krzyzosiak A., Sigurdardottir A., Bertolotti A.
Mol Cell. Aug 21;55(4):566-77

Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice
Krzyzosiak A., Szyszka-Niagolov M., Wietrzych M., Gobaille S., Muramatsu S., Krezel W.
Neuron. Jun 24,66(6):908-20