Grupa badawcza wirusologii ilościowej

Publikacje

2024

Wiśniewski, J., K. Więcek, H. Ali., K. Pyrc, A. Kula-Pãcurar, M. Wagner, H.-C., Chen. 2024. Distinguishable topological properties of functional genome networks in HIV-1 reservoirs. iScience DOI:10.1016/j.isci.2024.11122.
Tsalsabila, A., V.A. Dabur, I.J. Budiarso, S. Wustoni, H.-C. Chen, M.D. Birowosuto, A. Wibowo, S. Zeng. 2024. Progress and Outlooks in Designing Photonic Biosensor for Virus Detection. Adv Opt Mater. DOI:10.1002/adom.202400849.

2023

Thenin-Houssier, S., S. Machida, C. Jahan, J. Bonnet-Madin, S. Abbou, H.-C. Chen, R. Tesfaye, O. Cuvier, and M. Benkirane. 2023. POLE3 is a transcriptional repressor of unintegrated linear HIV-1 DNA required for efficient virus integration and escape from innate immune sensing. Sci. Adv. DOI:10.1126/sciadv.adh3642.
Więcek, K., and Chen, H.-C. 2023. Understanding latent HIV-1 reservoirs through host genomics approaches. iScience DOI:10.1016/j.isci.2023.108342.
Chen, H.-C. 2023. A systematic review of the barcoding strategy that contributes to COVID-19 diagnostics at a population level. Front. Mol. Biosci.DOI:10.3389/fmolb.2023.1141534.
Chen, H.-C. 2023. The Dynamic Linkage between Provirus Integration Sites and the Host Functional Genome Property Alongside HIV-1 Infections Associated with Antiretroviral Therapy. Vaccines. DOI: 10.3390/vaccines11020402.

2022

Chen, H.-C. 2022. Position matters – a discussion of HIV gene expression (中文主題名稱：原來擺對位置很重要 — 淺談人類免疫缺陷病毒的基因表現). Science Education Monthly (科學教育月刊). ISSN 1021-3708 ISSN 1021-3708, 454, P25-32, DOI:10.6216/SEM

2021

Lucic, B.*, H.-C. Chen*, M. Kuzman*, E. Zorita*, J. Wegner, V. Minneker, W. Wang, R. Fronza, M. Schmidt, and R. Stadhouders, V. Roukos, K. Vlahovicek, G. Filion and M. Lusic. 2019. Author Correction: Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. Nat. Communications. doi.org/10.1038/s41467-021-26471-w (*Shared first authors)

2020

Vansant*, G., H.-C. Chen*, E. Zorita, Trejbalová, K., Miklík, D., G. Filion, and Z. Debyser. 2020. The chromatin landscape at the HIV-1 provirus integration site determines viral expression. Nucleic Acids Research. doi.org/10.1093/nar/gkaa536 (*Shared first authors)
Machida, S., D. Depierre, H.-C. Chen, S. Houssier, G. Petitjean, C. Doyen, M. Takaku, O. Cuvier and M. Benkirane. 2020. Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome. PNAS. doi: 10.1073/pnas.1913754117

2019

Lucic, B.*, H.-C. Chen*, M. Kuzman*, E. Zorita*, J. Wegner, V. Minneker, W. Wang, R. Fronza, M. Schmidt, and R. Stadhouders, V. Roukos, K. Vlahovicek, G. Filion and M. Lusic. 2019. Spatially clustered loci with multiple enhancers are frequent targets of HIV-1. Nat. Communications. doi: 10.1038/s41467-019-12046-3 (*Shared first authors)

2018

Abner, E., M. Stoszko, L. Zeng, H.-C. Chen, A. Izquierdo-Bouldstridge, T. Konuma, E. Zorita, E. Fanunza, Q. Zhang, T. Mahmoudi, M.-M. Zhou, G. Filion, and A. Jordan. 2018. A new quinoline BRD4 inhibitor targets a distinct latent HIV-1 reservoir for re-activation from other ‘shock’ drugs. J Virol. doi: 10.1128/JVI.02056-17
Chen, H.-C.*, E. Zorita, and G. Filion*. 2018. Using Barcoded HIV Ensembles (B-HIVE) for single provirus transcriptomics. Curr Protoc Mol Biol. doi: 10.1002/cpmb.56 (*Corresponding authorship)

2017

Chen, H.-C., J.P. Martinez, E. Zorita, A. Meyerhans, and G. Filion. 2017. Position effects influence HIV latency reversal. Nat Struct Mol Biol. doi: 10.1038/nsmb.3328.

2015

Corrales, M., P. Cusco, D.R. Usmanova, H.-C. Chen, N.S. Bogatyreva, G.J. Filion, and D.N. Ivankov. 2015. Machine learning: how much does it tell about protein folding rates? PLoS One. doi:10:e0143166.

2008

Chen, P.M., H.-C. Chen, C.T. Ho, C.J. Jung, H.T. Lien, J.Y. Chen, and J.S. Chia. 2008. The two-component system ScnRK of Streptococcus mutans affects hydrogen peroxide resistance and murine macrophage killing. Microbes and Infection. doi:10:293-301.